
New Biology of Sex Differences study using our Digital Ventilated Cage (DVC®) shows female APP23 Alzheimer’s mice become ≈20 % more active and burn extra energy 3–4 months before any amyloid plaques, driving a three‑fold rise in early deaths.
BioMed Central Continuous, hands-off DVC monitoring captured the shift days in advance, confirming its value for early behavioural biomarkers and stress-free, 24/7 data collection.