News

Sex-specific changes in energy demand during the preplaque stage in a transgenic Alzheimer’s mouse model

Sex-specific changes in energy demand during the preplaque stage in a transgenic Alzheimer’s mouse model
// 26 August 2025

New Biology of Sex Differences study using our DigitalVentilatedCage (DVC®) shows female APP23 Alzheimer’s mice become ≈20 % more active and burn extra energy 3–4 months before any amyloid plaques, driving a three‑fold rise in early deaths. 

BioMed Central Continuous, hands-off DVC monitoring captured the shift days in advance, confirming its value for early behavioural biomarkers and stress-free, 24/7 data collection.

Read the open-access-article.


<< News Archive