Fatal familial insomnia (FFI) is a rare genetic degenerative brain disorder. A recent study used the DVC® technology to assess whether, in an non-invasive manner, a change in resting/sleep pattern would occur.
In fact, thanks to the DVC® changes at circadian rhythm were detected in which FFI mice showed decreased activity.
In part motor dysfunction and rescued deficits were rescued via doxycycline but not the disease progression. Through the DVC® the researchers were able to identify the disease progression and its partial amelioration but not in standard test as Rotarod.