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A new interesting webinar on DVC® Data Analysis! Have a look what the GSK team have done

A new interesting webinar on DVC®  Data Analysis! Have a look what the GSK team have done
// 13 May 2021

We are pleased to share another interesting webinar with you, it is entitled “PSI ToxSIG Webinar: Beyond the looking glass - Interpreting animal welfare & behaviour by monitoring & assessing mice activity data” and was presented at the PSI ToxSIG conference The focus of this webinar is on the Analytical platform of the  DVC® and the data analysis.

The presenters, from GSK, will show and explain how to use and analyze the data get from the DVC® system regards to translational research, data replicability and animal welfare.

In this webinar, Joanna Moore (Global Laboratory Animal Medicine) will discuss how home cage monitoring can be used to reduce animal stress, optimize methodology and guide physiology and animal behaviour research, while Eloisa Brook and George Birkbeck (Dev Biostats NCTS Research Stats) explain how they initially evaluated the data followed by using Functional data analysis to get a more precise answer to the research question. Within the presentation the team will highlight some interesting mouse behaviour findings and the 3Rs benefits of including the DVC® in animal research.

For more information or to watch to the webinar click here https://www.psiweb.org/vod/item/psi-toxsig-webinar-beyond-the-looking-glass---interpreting-animal-welfare-behaviour-by-monitoring-assessing-mice-activity-data 

Abstract

Typically, animal welfare and behaviour are monitored and assessed visually at periodic times throughout the day. However, in order to go beyond this level of assessment we have been using the Digital Ventilated Cage (DVC®) to capture this information quantitively. The DVC® is a non-invasive Home Cage Monitoring system that uses electromagnetic sensors to track and monitor the cage activity. Research Statistics advised on study designs, protocols and carried out extensive exploratory and further statistical analyses on the data. This webinar will give an overview of the system and the data collected, along with the benefits gained from continuous cage monitoring using the DVC®. We will use a case study to highlight some of the key discussion points in this presentation. All animal studies were ethically reviewed and carried out in accordance with the Animals (Scientific Procedures) Act 1986 and the GSK Policy on the Care, Welfare and Treatment of Animals.

Key topics of the webinar include:

  • Using home cage activity as a readout for animal welfare
  • Using locomotor activity to optimize methodology and validate study design in real-time
  • Analyze the data downloaded from the system
  • Find new way to get new and useful biomarker form the data collected

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